As maps4gps said, 4GB is supported if you upgrade your firmware, and since they only cost about the price of two 2GB cards they offer more flexibility. I updated using the WebUpdater with my old Sirf 60CSX and have no regrets. Large file transfers will be HOURS faster if you use a card reader instead of any form of transfer to your GPS, since the GPS is only USB 1.5 or something like that instead of USB2. Be sure you get a card reader that supports SDHC. A 4GB microSD card is about $8 at Amazon or Buy.com. Same price for a USB2 mini card reader.